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Cat. No. Product Name Information
PC-60208

BI 409306

PDE9A inhibitor

BI 409306 (SUB 166499) is a potent and selective inhibitor of human and rat PDE9A with IC50 of 65 nM and 168 nM, respectively.
PC-60206

PF-4181366

PDE9A inhibitor

PF-4181366 (PF-04181366) is a potent, selective, brain penetrant PDE9A inhibitor with IC50 of 1.8 nM.
PC-60205

PF-04447943

PDE9A inhibitor

PF-04447943 (Edelinontrine) is a potent, selective, brain penetrant, orally active PDE9A inhibitor with IC50 of 8.3 nM.
PC-60093

PDE5-IN-6c

A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1.
PC-42212

R 80123

PDE inhibitor

R 80123 is the Z-isomer of R 79595, a highly selective PDE inhibitor, 10-fold more potent than R 79595.
PC-46014

Tadalafil

PDE5 inhibitor

Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM).
PC-46013

Nortadalafil

PDE5 inhibitor

Nortadalafil (Demethyl Tadalafil) is demethyl tadalafil, a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction (ED)..
PC-42219

Roflumilast Impurity E

PDE4 inhibitor

Roflumilast Impurity E (3-O-Decyclopropyl Roflumilast) is an impurity of Roflumilast, which is a selective and long-acting inhibitor of PDE-4 with IC50 value of 0.8 nM.
PC-45952

GSK256066 trifluoroacetate

PDE4 inhibitor

GSK256066 trifluoroacetate is a potent, selective PDE4 inhibitor with pIC50 of 11.5, 11.3, 11.4, and 11.9 for PDE4B, A, C, and D, respectively.
PC-42211

Revizinone

PDE3 inhibitor

Revizinone (R80122) is a potent, selective PDE3 inhibitor with IC50 of 36 nM, displays >20,000-fold selectivity over PDE1.
PC-42399

PDE1-IN-2

PDE1C inhibitor

PDE1-IN-2 is a potent, selective PDE1C inhibitor with IC50 of 6 nM, weakly inhibits PDE1B and PDE1A with IC50 of 140 and 164 nM, respectvely.
PC-45080

Rolipram

PDE4 inhibitor

Rolipram (SB95952, ZK62711) is a potent, selective inhibitor of phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.

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