| Cat. No. |
Product Name |
Information |
| PC-60208 |
BI 409306
PDE9A inhibitor
|
BI 409306 (SUB 166499) is a potent and selective inhibitor of human and rat PDE9A with IC50 of 65 nM and 168 nM, respectively. |
| PC-60205 |
PF-04447943
PDE9A inhibitor
|
PF-04447943 (Edelinontrine) is a potent, selective, brain penetrant, orally active PDE9A inhibitor with IC50 of 8.3 nM. |
| PC-60093 |
PDE5-IN-6c
|
A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1. |
| PC-46014 |
Tadalafil
PDE5 inhibitor
|
Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM). |
| PC-46013 |
Nortadalafil
PDE5 inhibitor
|
Nortadalafil (Demethyl Tadalafil) is demethyl tadalafil, a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction (ED).. |
| PC-42219 |
Roflumilast Impurity E
PDE4 inhibitor
|
Roflumilast Impurity E (3-O-Decyclopropyl Roflumilast) is an impurity of Roflumilast, which is a selective and long-acting inhibitor of PDE-4 with IC50 value of 0.8 nM. |
| PC-45282 |
Cilostazol
PDE3 inhibitor
|
Cilostazol (OPC 13013, OPC 21) is a potent, selective inhibitor of PDE3A with IC50 of 0.2 uM. |
| PC-42698 |
Cilomilast
PDE4 inhibitor
|
Cilomilast (SB207499) is a potent and selective PDE4 inhibitor with IC50 of 95/120 nM for LPDE4/HPDE4. |
| PC-45821 |
PF-2545920
PDE10A inhibitor
|
PF-2545920 (Mardepodect) is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
| PC-22654 |
PDE4B/PDE5A inhibitor MDL3
PDE4B/PDE5A inhibitor
|
MDL3 is a potent, dual inhibitor of PDE4B and PDE5A, ameliorates pathophysiological signs and symptoms of liver injury and inflammation. |
| PC-22040 |
YM976
PDE4 inhibitor
|
YM976 is a potent, selective phosphodiesterase type 4 (PDE4) inhibitor with IC50 of 2.2 nM against PDE4 purified from human peripheral leukocytes. |
| PC-22039 |
BAY 60-7550
PDE2 inhibitor
|
BAY 60-7550 (Bay60-7550) is a potent and selective PDE2 inhibitor with Ki of 3.8 nM, IC50 of 4.7 nM (human PDE2A), and 2.0 nM (bovine purified PDE2). |
