| Cat. No. |
Product Name |
Information |
| PC-60208 |
BI 409306
PDE9A inhibitor
|
BI 409306 (SUB 166499) is a potent and selective inhibitor of human and rat PDE9A with IC50 of 65 nM and 168 nM, respectively. |
| PC-60205 |
PF-04447943
PDE9A inhibitor
|
PF-04447943 (Edelinontrine) is a potent, selective, brain penetrant, orally active PDE9A inhibitor with IC50 of 8.3 nM. |
| PC-60093 |
PDE5-IN-6c
|
A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1. |
| PC-46014 |
Tadalafil
PDE5 inhibitor
|
Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM). |
| PC-46013 |
Nortadalafil
PDE5 inhibitor
|
Nortadalafil (Demethyl Tadalafil) is demethyl tadalafil, a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction (ED).. |
| PC-42219 |
Roflumilast Impurity E
PDE4 inhibitor
|
Roflumilast Impurity E (3-O-Decyclopropyl Roflumilast) is an impurity of Roflumilast, which is a selective and long-acting inhibitor of PDE-4 with IC50 value of 0.8 nM. |
| PC-45282 |
Cilostazol
PDE3 inhibitor
|
Cilostazol (OPC 13013, OPC 21) is a potent, selective inhibitor of PDE3A with IC50 of 0.2 uM. |
| PC-42698 |
Cilomilast
PDE4 inhibitor
|
Cilomilast (SB207499) is a potent and selective PDE4 inhibitor with IC50 of 95/120 nM for LPDE4/HPDE4. |
| PC-45821 |
PF-2545920
PDE10A inhibitor
|
PF-2545920 (Mardepodect) is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
| PC-23243 |
Senazodan hydrochloride
PDE3 inhibitor
|
Senazodan (MCI-154) hydrochloride is a small molecule Ca2+-sensitiser and PDE3 inhibitor, exerts positive inotropic and chronotropic effects by binding directly to troponin C. |
| PC-23242 |
Pimobendan
PDE3 inhibitor
|
Pimobendan (UD-CG115) is an oral Ca2+-sensitiser and PDE3 inhibitor (IC50=320 nM). |
| PC-23191 |
PDE11A4 inhibitor 14b
PDE11A4 inhibitor
|
PDE11A4 inhibitor 14b is a potent, selective PDE11A4 inhibitor with IC50 of 53 nM, cAMP EC50 of 4.3 uM. |
