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Request The Product List ofPhosphodiesterase (PDE) Phosphodiesterase (PDE)

Cat. No. Product Name Information
PC-25003

PDE10A inhibitor 3e

PDE10A inhibitor

PDE10A inhibitor 3e is a potent, selective phosphodiesterase 10A (PDE10A) inhibitor with IC50 of 6.5 nM, >95-fold selective over other PDEs.
PC-25002

Ibudilast

PDE inhibitor

Ibudilast (KC-404, AV-411, MN-166) is a neuroimmune modulator which selectively inhibits phosphodiesterases (PDE) 3, PDE4, PDE10, and PDE11, shows platelet anti-aggregatory effects.
PC-24966

AWD 12-281

PDE4 inhibitor

AWD 12-281 (GW 842470) is a potent, orally active and highly selective phosphodiesterase 4 (PDE4) inhibitor with IC50 of 9.7 nM.
PC-24965

LEO 29102

PDE4 inhibitor

LEO 29102 is a potent, selective, and soft-drug PDE4 inhibitor with IC50 of 5 nM (PDE4D), inhibits TNFα release from hPBMCs stimulated with LPS with IC50 of 16 nM.
PC-24964

LEO 39652

PDE4 inhibitor

LEO 39652 is a potent, selective PDE4 inhibitor with IC50 of 1.2/1.2/3.0/3.8 nM for PDE4A/B/C/D respectively, selective over other PDE subtypes.
PC-24956

PF-07038124 hydrochloride

PDE4B2 inhibitor

Idrebormilast hydrochloride (PF-07038124) is a highly potent, selective PDE4 inhibitor with IC50 of 0.5 nM for PDE4B2 in SPA assays.
PC-24217

TP-10

PDE10A inhibitor

TP-10 is a potent, selective inhibitor of cyclic nucleotide phosphodiesterase PDE10A with IC50 of 0.8 nM.
PC-23896

PDE7A inhibitor 26

PDE7A inhibitor

PDE7A inhibitor 26 is a potent, selective PDE7A inhibitor with IC50 of 3.7 nM, 54-fold selective over PDE7B.
PC-23575

Dipyridamole

PDE inhibitor, Ferroptosis inhibitor

Dipyridamole is an orally active phosphodiesterase (PDE) inhibitor, also is a potent inhibitor of ferroptosis in pulmonary epithelial and endothelial cells, binds to and activates superoxide dismutase 1 (SOD1).
PC-23488

PDE8 inhibitor 15

PDE8 inhibitor

PDE8 inhibitor 15 is a potent, selective phosphodiesterase 8A (PDE8A) inhibitor with IC50 of 11 nM (PDE8A), high selectivity over other PDEs.
PC-23487

PDE8A inhibitor 3a

PDE8 inhibitor

PDE8A inhibitor 3a is a potent, selective phosphodiesterase 8A (PDE8A) inhibitor with IC50 of 10 nM, >220-fold selective over PDE1B, PDE3A, PDE5A1, PDE7A1, PDE9A2, and PDE11A4.
PC-23485

VP1.15

PDE7/GSK-3 inhibitor

VP1.15 is a potent, dual PDE7/GSK-3 inhibitor with IC50 of 1.1 (PDE7) and 1.95 uM (GSK-3), shows antipsychotic and cognitive capacities.

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