| Cat. No. |
Product Name |
Information |
| PC-25003 |
PDE10A inhibitor 3e
PDE10A inhibitor
|
PDE10A inhibitor 3e is a potent, selective phosphodiesterase 10A (PDE10A) inhibitor with IC50 of 6.5 nM, >95-fold selective over other PDEs. |
| PC-25002 |
Ibudilast
PDE inhibitor
|
Ibudilast (KC-404, AV-411, MN-166) is a neuroimmune modulator which selectively inhibits phosphodiesterases (PDE) 3, PDE4, PDE10, and PDE11, shows platelet anti-aggregatory effects. |
| PC-24966 |
AWD 12-281
PDE4 inhibitor
|
AWD 12-281 (GW 842470) is a potent, orally active and highly selective phosphodiesterase 4 (PDE4) inhibitor with IC50 of 9.7 nM. |
| PC-24965 |
LEO 29102
PDE4 inhibitor
|
LEO 29102 is a potent, selective, and soft-drug PDE4 inhibitor with IC50 of 5 nM (PDE4D), inhibits TNFα release from hPBMCs stimulated with LPS with IC50 of 16 nM. |
| PC-24964 |
LEO 39652
PDE4 inhibitor
|
LEO 39652 is a potent, selective PDE4 inhibitor with IC50 of 1.2/1.2/3.0/3.8 nM for PDE4A/B/C/D respectively, selective over other PDE subtypes. |
| PC-24956 |
PF-07038124 hydrochloride
PDE4B2 inhibitor
|
Idrebormilast hydrochloride (PF-07038124) is a highly potent, selective PDE4 inhibitor with IC50 of 0.5 nM for PDE4B2 in SPA assays. |
| PC-24217 |
TP-10
PDE10A inhibitor
|
TP-10 is a potent, selective inhibitor of cyclic nucleotide phosphodiesterase PDE10A with IC50 of 0.8 nM. |
| PC-23896 |
PDE7A inhibitor 26
PDE7A inhibitor
|
PDE7A inhibitor 26 is a potent, selective PDE7A inhibitor with IC50 of 3.7 nM, 54-fold selective over PDE7B. |
| PC-23575 |
Dipyridamole
PDE inhibitor, Ferroptosis inhibitor
|
Dipyridamole is an orally active phosphodiesterase (PDE) inhibitor, also is a potent inhibitor of ferroptosis in pulmonary epithelial and endothelial cells, binds to and activates superoxide dismutase 1 (SOD1). |
| PC-23488 |
PDE8 inhibitor 15
PDE8 inhibitor
|
PDE8 inhibitor 15 is a potent, selective phosphodiesterase 8A (PDE8A) inhibitor with IC50 of 11 nM (PDE8A), high selectivity over other PDEs. |
| PC-23487 |
PDE8A inhibitor 3a
PDE8 inhibitor
|
PDE8A inhibitor 3a is a potent, selective phosphodiesterase 8A (PDE8A) inhibitor with IC50 of 10 nM, >220-fold selective over PDE1B, PDE3A, PDE5A1, PDE7A1, PDE9A2, and PDE11A4. |
| PC-23485 |
VP1.15
PDE7/GSK-3 inhibitor
|
VP1.15 is a potent, dual PDE7/GSK-3 inhibitor with IC50 of 1.1 (PDE7) and 1.95 uM (GSK-3), shows antipsychotic and cognitive capacities. |
