| Cat. No. |
Product Name |
Information |
| PC-60657 |
GSK356278
PDE4 inhibitor
|
GSK356278 is a potent, selective, brain-penetrant and orally bioavailable phosphodiesterase 4 (PDE4) inhibitor with pIC50 of 8.8 (PDE4B). |
| PC-60651 |
AMG 580
PDE10A inhibitor
|
AMG 580 (AMG580) is a novel potent, selective phosphodiesterase 10A (PDE10A) inhibitor with IC50 of 0.13 nM. |
| PC-60608 |
(S)-C33
PDE9A inhibitor
|
(S)-C33 is a potent, selective PDE9A inhibitor with IC50 of 11 nM, >45-fold selectivity over other PDE isoforms. |
| PC-60564 |
PF 05180999
PDE2A inhibitor
|
PF-05180999 (PF 5180999) is a potent, selective, brain-penetrating and orally bioavailable phosphodiesterase 2A (PDE2A) inhibitor with IC50 of 1 nM. |
| PC-60563 |
TAK-915
PDE2A inhibitor
|
TAK-915 (TAK915) is a highly potent, selective, brain-penetrating and orally active phosphodiesterase 2A (PDE2A) inhibitor with IC50 of 0.61 nM. |
| PC-60496 |
AMG 579
PDE10A inhibitor
|
AMG 579 (AMG579) is a potent, selective, CNS penetrant, orally bioavailable PDE10A inhibitor with IC50 of 0.1 nM. |
| PC-60365 |
PDM-631
PDE2A inhibitor
|
PDM-631 is a potent, selective, brain-penetrable and orally active PDE2A inhibitor with IC50 of 1.5 and 4.2 nM for human and rat PDE2A, respectively. |
| PC-60220 |
Ensifentrine
PDE3/PDE4 inhibitor
|
RPL-554 (Ensifentrine, LS-193855, RPL554) is a potent, orally available, dual PDE3/PDE4 inhibitor with IC50 of 0.4 nM and 1479 nM, respectively. |
| PC-60211 |
GS-5759
PDE4 inhibitor, β2-adrenoceptor agonist
|
GS-5759 is a novel bifunctional PDE4 inhibitor (IC50=5 nM) and long acting β2-adrenoceptor agonist (EC50=8 nM). |
| PC-60208 |
BI 409306
PDE9A inhibitor
|
BI 409306 (SUB 166499) is a potent and selective inhibitor of human and rat PDE9A with IC50 of 65 nM and 168 nM, respectively. |
| PC-60206 |
PF-4181366
PDE9A inhibitor
|
PF-4181366 (PF-04181366) is a potent, selective, brain penetrant PDE9A inhibitor with IC50 of 1.8 nM. |
| PC-60205 |
PF-04447943
PDE9A inhibitor
|
PF-04447943 (Edelinontrine) is a potent, selective, brain penetrant, orally active PDE9A inhibitor with IC50 of 8.3 nM. |
