| Cat. No. |
Product Name |
Information |
| PC-60496 |
AMG 579
PDE10A inhibitor
|
AMG 579 (AMG579) is a potent, selective, CNS penetrant, orally bioavailable PDE10A inhibitor with IC50 of 0.1 nM. |
| PC-60365 |
PDM-631
PDE2A inhibitor
|
PDM-631 is a potent, selective, brain-penetrable and orally active PDE2A inhibitor with IC50 of 1.5 and 4.2 nM for human and rat PDE2A, respectively. |
| PC-60220 |
Ensifentrine
PDE3/PDE4 inhibitor
|
RPL-554 (Ensifentrine, LS-193855, RPL554) is a potent, orally available, dual PDE3/PDE4 inhibitor with IC50 of 0.4 nM and 1479 nM, respectively. |
| PC-60211 |
GS-5759
PDE4 inhibitor, β2-adrenoceptor agonist
|
GS-5759 is a novel bifunctional PDE4 inhibitor (IC50=5 nM) and long acting β2-adrenoceptor agonist (EC50=8 nM). |
| PC-60208 |
BI 409306
PDE9A inhibitor
|
BI 409306 (SUB 166499) is a potent and selective inhibitor of human and rat PDE9A with IC50 of 65 nM and 168 nM, respectively. |
| PC-60206 |
PF-4181366
PDE9A inhibitor
|
PF-4181366 (PF-04181366) is a potent, selective, brain penetrant PDE9A inhibitor with IC50 of 1.8 nM. |
| PC-60205 |
PF-04447943
PDE9A inhibitor
|
PF-04447943 (Edelinontrine) is a potent, selective, brain penetrant, orally active PDE9A inhibitor with IC50 of 8.3 nM. |
| PC-60093 |
PDE5-IN-6c
PDE5 inhibitor
|
PDE5-IN-6c is a potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1. |
| PC-42212 |
R 80123
PDE inhibitor
|
R 80123 is the Z-isomer of R 79595, a highly selective PDE inhibitor, 10-fold more potent than R 79595. |
| PC-46014 |
Tadalafil
PDE5 inhibitor
|
Tadalafil (IC-351, IC351) is a potent, selective phosphodiesterase-5 (PDE5) inhibitor (IC50=1 nM). |
| PC-46013 |
Nortadalafil
PDE5 inhibitor
|
Nortadalafil (Demethyl Tadalafil) is demethyl tadalafil, a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction (ED).. |
| PC-42219 |
Roflumilast Impurity E
PDE4 inhibitor
|
Roflumilast Impurity E (3-O-Decyclopropyl Roflumilast) is an impurity of Roflumilast, which is a selective and long-acting inhibitor of PDE-4 with IC50 value of 0.8 nM. |
