| Cat. No. |
Product Name |
Information |
| PC-45736 |
AN3199
PDE4 inhibitor
|
AN3199 is a potent PDE4 inhibitor with IC50 of 94.5 nM. |
| PC-42760 |
Crisaborole
PDE4 inhibitor
|
Crisaborole (AN-2728) is a potent PDE4 inhibitor with IC50 of 0.49 uM. |
| PC-45282 |
Cilostazol
PDE3 inhibitor
|
Cilostazol (OPC 13013, OPC 21) is a potent, selective inhibitor of PDE3A with IC50 of 0.2 uM. |
| PC-45441 |
Udenafil
PDE5 inhibitor
|
Udenafil (DA-8159) is a potent and selective phosphodiesterase 5 (PDE5) inhibitor, inhibits PDE5 activity in rabbit and human platelets with IC50 of 5.84 nM and 8.2 nM, respectively. |
| PC-42698 |
Cilomilast
PDE4 inhibitor
|
Cilomilast (SB207499) is a potent and selective PDE4 inhibitor with IC50 of 95/120 nM for LPDE4/HPDE4. |
| PC-45822 |
PF-2545920 hydrochloride
PDE10A inhibitor
|
PF-2545920 hydrochloride (Mardepodect) potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
| PC-45821 |
PF-2545920
PDE10A inhibitor
|
PF-2545920 (Mardepodect) is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
| PC-45440 |
Avanafil
PDE5 inhibitor
|
Avanafil (TA1790) is a potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction. |
| PC-42235 |
SCH00013
Cardiotonic agent
|
SCH00013 is a cardiotonic agent that acts as a calcium sensitizer with no chronotropic activity in mammalian cardiac muscle, elicits positive inotropic effect in dog and rabbit ventricular muscles (EC50=9.2 uM). |
| PC-23410 |
PDE1 inhibitor 3f
PDE1 inhibitor
|
PDE1 inhibitor 3f is a potent, selective PDE1 inhibitor with IC50 of 11 nM, >24-fold selectivity over other PDEs, shows antifibrotic effects in vivo and in vitro. |
| PC-23407 |
Vardenafil
PDE5 inhibitor
|
Vardenafil is a potent, selective and orally active inhibitor of phosphodiesterase-5 (PDE5), inhibits the hydrolysis of cGMP by PDE5 with IC50 of 0.7 nM. |
| PC-23406 |
RF26
PDE5 inhibitor
|
RF26 (Compound d12) is a highly potent and selective PDE5 inhibitor with IC50 of 1 nM, three times more potent than sildenafil and more selective with a selectivity index of >10,000-fold against all other PDE isozymes. |
