| Cat. No. |
Product Name |
Information |
| PC-25209 |
YQA14
D3R antagonist
|
YQA14 is a potent, selective D3 dopamine receptor (D3R) antagonist with Ki of 0.68 nM, shows no affinity for D2R. |
| PC-24329 |
Cariprazine
D3 receptor agonist
|
Cariprazine (RGH-188) is an antipsychotic compound that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). |
| PC-23120 |
SB-277011 hydrochloride
D3R antagonist
|
SB-277011 hydrochloride (SB-277011A) is a potent and selective dopamine D3 receptor antagonist with pKi of 8.0. |
| PC-23107 |
PF-06412562
D1R agonist
|
PF-06412562 (PF-2562, CVL-562) is a potent, selective non-catechol dopamine D1R agonist with Ki of 113 nM and EC50 of 568 nM, Emax 44%, PF-06412562 is a selective D1/D5 dopamine receptor partial agonist. |
| PC-21487 |
Nemonapride
D2R antagonist
|
Nemonapride (YM-09151-2) is a highly potent, selective dopamine D2 receptor (D2R) antagonist with Ki of 0.06 nM, also activates 5-HT1A receptor with IC50 of 34 nM, shows antipsychotic effect. |
| PC-21106 |
L-745870
D4R inhibitor
|
L-745870 (L-745,870) is is a potent, selective, brain-penetrant and orally active dopamine D4 receptor (D4R) antagonist with Ki of 0.43 nM. |
| PC-21084 |
Lurasidone hydrochloride
D2R antagonist
|
Lurasidone hydrochloride (SM-13496) is an atypical antipsychotic compound with potent dopamine D2 (Ki =1.68 nM) and serotonin 5-HT2A (Ki=2.03 nM) receptor-blocking activities. |
| PC-21083 |
Lurasidone
D2R antagonist
|
Lurasidone (SM-13496) is an atypical antipsychotic compound with potent dopamine D2 (Ki =1.68 nM) and serotonin 5-HT2A (Ki=2.03 nM) receptor-blocking activities. |
| PC-20865 |
GR 103691
D3 receptor antagonist
|
GR 103691 is a potent, selective dopamine D3 receptor antagonist with binding Ki of 0.4 nM, >100-fold selectivity over D1 and D4 receptors. |
| PC-20863 |
NGB2904
D3R antagonist
|
NGB2904 (NGB 2904) is a potent, highly selective dopamine D3 receptor (D3R) antagonist with Ki of 2.0 nM for hD3, 56-fold selectivity over hD2. |
| PC-20862 |
PG01037
D3 receptor antagonist
|
PG01037 is a potent selective dopamine D3 receptor (D3R) antagonist with binding Ki of 0.7 nM, displays 133- and 540-fold selectivity over D2 and D4 receptors, respectively. |
| PC-20169 |
AG-0029
D2/D3 agonist/H3 antagonist
|
AG-0029 is a highly potent agonist of dopamine D2/D3 receptor (EC50=0.08 nM) and a moderate affinity antagonis of H3 receptor (IC50=111 nM). |
