| Cat. No. |
Product Name |
Information |
| PC-72875 |
MJM-1
HDAC inhibitor
|
MJM-1 is a small-molecule brain-penetrant HDAC inhibitor that increases the overall level of histone 3 (H3) acetylation in prostate cancer cell line. |
| PC-72740 |
NN-390
HDAC6 inhibitor.
|
NN-390 (NN390) is a potent, selective HDAC6 inhibitor with IC50 of 9.8 nM, >200-550-fold selectivity over other HDAC isoforms. |
| PC-72144 |
Splitomicin
Sir2p inhibitor
|
Splitomicin is a selective Sir2p inhibitor, inhibits NAD+-dependent histone deacetylase activity (HDA) of the Sir2 protein wqith IC50 of 60 uM. |
| PC-72095 |
FT234
HDAC11 inhibitor
|
FT234 (FT-234) is a selective HDAC11 inhibitor. |
| PC-35666 |
Class I and IIB HDAC inhibitor 42
|
Class I and IIB HDAC inhibitor 42 is a novel potent, selective class I and IIB inhibitor (HDAC1 Ki=0.27 nM) for topical treatment of cutaneous t-cell lymphoma.. |
| PC-35369 |
SALL4 peptide FFW
|
SALL4 peptide FFW (RRKFAKFQWI, FFW peptide) is a potent therapeutic SALL4 peptide antagonist of SALL4-NURD (nucleosome remodeling deacetylase) interaction with target affinity of 23 nM. |
| PC-63481 |
HDAC8-IN-22d
|
HDAC8-IN-22d is a potent, selective HDAC8 inhibitor with IC50 of 27.2 nM, exhibits no activity against other HDACs and limited activity against HDAC1 and 3. |
| PC-63458 |
Remodelin Fluor
|
Remodelin Fluor is a small molecule analog of Remodelin, demonstrates in vivo activitiy against NAT10, significantly enhances the healthspan in a Lmna G609G HGPS mouse model.. |
| PC-45618 |
Pimelic Diphenylamide 106
|
A slow, tight-binding inhibitor of class I HDACs (HDAC1/2/3, Ki=148/102/14 nM respectively). |
| PC-45052 |
Remodelin hydrobromide
|
A potent inhibitor of the acetyl-transferase protein NAT10 that acetylates both histones and microtubules. |
| PC-44034 |
Resminostat
|
A potent inhibitor of HDAC1/3/6 with IC50s of 43-72 nM. |
| PC-42249 |
HDAC-IN-4
|
A histone deacetylase (HDAC) inhibitor, extracted from patent WO/2007045844 A1.. |
