| Cat. No. |
Product Name |
Information |
| PC-21553 |
TDI-8304
Pf20S inhibitor
|
TDI-8304 is a highly selective, macrocyclic peptide inhibitor of malaria parasite Plasmodium falciparum proteasome (Pf20S) with IC50 of 0.06 uM, shows high potency against P. falciparum strain Pf 3D7 (EC50=0.009 uM). |
| PC-21022 |
OSM-S-106
PfAsnRS inhibitor
|
OSM-S-106 is a reaction hijacking inhibitor of Plasmodium falciparum asparagine tRNA synthetase (PfAsnRS), inhibits the 3D7 line of P. falciparum with IC50 of 58 nM. |
| PC-20446 |
Nemacol-1
VAChT inhibitor
|
Nemacol-1 is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter (VAChT), demonstrates nematode-selective activity (C. elegans, EC50=7.1 uM). |
| PC-20297 |
P4Q-391
P.f Cyt bc1 inhibitor
|
P4Q-391 is an antimalarial agent with selective inhibition of the parasite's coenzyme Q cycle, inhibits mitochondrial cytochrome bc1 complex (Cyt bc1). |
| PC-20296 |
ELQ-300
P.f Cyt bc1 inhibitor
|
ELQ-300 (ELQ300) is a potent, selective inhibitor of P. falciparummitochondrial cytochrome bc1 complex with IC50 of 0.56 nM. |
| PC-20295 |
ELQ-331
P.f Cyt bc1 inhibitor
|
ELQ-331 (ELQ331) is an alkoxycarbonate prodrug of antimalarial compound ELQ-300 (P. falciparum cytochrome bc1 complex inhibitor), shows P. falciparum IC50 of 6 nM. |
| PC-20294 |
GSK932121
P.f Cyt bc1 inhibitor
|
GSK932121 is a potent, selective inhibitor of P. falciparum cytochrome bc1 with IC50 of 7 nM, binds to Qi site of cytochrome bc1 and shows potent antimalarial activity in vitro and in vivo. |
| PC-20293 |
GW844520
P.f Cyt bc1 inhibitor
|
GW844520 is a potent, selective inhibitor of P. falciparum cytochrome bc1 with IC50 of 2 nM, binds to Qi site of cytochrome bc1 and shows potent antimalarial activity. |
| PC-20289 |
WJM228
P.f Cyt bc1 inhibitor
|
WJM228 (WJM-228) is a potent selective inhibitor of P. falciparum cytochrome bc1, targets the Qo site of cytochrome b (cyt b), shows potent parasite activity against P. falciparum 3D7 with EC50 of 19 nM. |
| PC-20266 |
Genz-667348
Pf DHODH inhibitor
|
Genz-667348 (Genz667348) is a potent, selective P. falciparum DHODH inhibitor with IC50 of 22, 14 and 42 nM for PfDHODH, PbDHODH and PvDHODH, respectively. |
| PC-20265 |
DSM502
Pf DHODH inhibitor
|
DSM502 (DSM 502) is a potent, selective inhibitor of P. falciparum and P. vivax DHODH with IC50 of 20 and 14 nM, respectively. |
| PC-20262 |
DSM267
DHODH inhibitor
|
DSM267 (DSM 267) is a potent, highly selective, long-duration and orally bioavailable malaria DHODH inhibitor. |
