| Cat. No. |
Product Name |
Information |
| PC-21579 |
HC-030031
TRPA1 inhibitor
|
HC-030031 is a potent, selective TRPA1 inhibitor, inhibits AITC- and formalin-evoked calcium influx with IC50s of 6.2 and 5.3 μM, respectively. |
| PC-21130 |
VPC01091.4
TRPM7 inhibitor
|
VPC01091.4 is a non-phosphorylatable FTY720 analogue and novel TRPM7 inhibitor, inhibits IM7 in a dose-dependent manner with IC50 of 0.665 uM. |
| PC-20743 |
SAR7334
TRPC6 inhibitor
|
SAR7334 (SAR-7334 ) is a highly potent and selective inhibitor of TRPC6 channel, reduces TRPC6-mediated Ca2+ influx with IC50 of 9.5 nM. |
| PC-20552 |
GsMTx4
TRPC1/6 inhibitor
|
GsMTx4 is a spider venom peptide that selectively inhibits cationic mechanosensitive channels (MSCs) such as TRPC1 and TRPC6 and Piezo channels, also blocks cation-selective stretch-activated channels (SACs). |
| PC-49536 |
TRPM5 agonist 39
TRPM5 agonist
|
TRPM5 agonist 39 is a potent, selective transient receptor potential cation channel subfamily M member 5 (TRPM5) agonist with pEC50 of 7.1, shows high selectivity over TRPA1, TRPV1, TRPV4, TRPM4 and TRPM8. |
| PC-49411 |
Trpvicin
TRPV3 inhibitor
|
Trpvicin is a potent and subtype-selective inhibitor of TRPV3 with IC50 of 0.41 and 0.22 uM for hTRPV3-WT and hTRPV3-G573S mutant, respectively. |
| PC-38809 |
GNE551
TRPA1 agonist
|
GNE551 is a potent, selective, non-covalent agonist of TRPA1 ion channel with EC50 of 254 nM in Ca2+ influx assays. |
| PC-73245 |
GFB-8438
TRPC5 inhibitor
|
GFB-8438 is a potent, selective TRPC5 inhibitor with IC50 of 0.18 uM (hTRPC5, Qpatch assay). |
| PC-73026 |
ML-SI3
TRPML1 antagonist
|
ML-SI3 (Mucolipin-specific synthetic inhibitor 3) is a synthetic antagonist of transient receptor potential mucolipin 1 (TRPML1), prevents lysosomal calcium efflux and blocks downstream TRPML1-mediated induction of autophagy. |
| PC-73025 |
ML-SA1
TRPML1 agonist
|
ML-SA1 (Mucolipin-specific synthetic agonist 1) is a potent synthetic agonist for TRPML1. |
| PC-72922 |
JW-65
TRPC3 inhibitor
|
JW-65 (JW65) is a selective, potent, CNS-permeable TRPC3 inhibitor improved stability compared to Pyr3. |
| PC-72599 |
GSK2798745
TRPV4 inhibitor
|
GSK2798745 (GSK-2798745) is a potent, selective TRPV4 inhibitor with IC50 of 1.8/1.6 nM (hTRPV4/rTRPV4). |
