| Cat. No. |
Product Name |
Information |
| PC-27884 |
YS2219
ENPP1 inhibitor
|
YS2219 is a highly potent and selective ENPP1 inhibitor with IC50 of 5.70 or 9.68 nM, shows weak inhibition against ENPP2 and ENPP3 (IC50>2500 nM). |
| PC-27883 |
YS3074
ENPP1 inhibitor
|
YS3074 is a potent and selective ENPP1 inhibitor with IC50 of 4.23 nM, shows weak to negligible ENPP2 and ENPP23 inhibition. |
| PC-27748 |
LW1646
PDE5 inhibitor
|
LW1646 is a potent, selective and orally available PDE5 inhibitor with IC50 of 1.09 nM, exerts antifibrotic effects. |
| PC-26398 |
MT-3014
PDE10A inhibitor
|
MT-3014 is a potent, highly selective PDE10A inhibitor with IC50 of 0.062 nM and 0.090 nM for human and bovine PDE10A, >1000-fold selective over other PDEs. |
| PC-26351 |
Prifemilast
PDE4 inhibitor
|
Prifemilast (HPP737) is a potent, selective, oral phosphodiesterase-4 (PDE4) inhibitor. |
| PC-26071 |
ADT-030
PDE10A inhibitor
|
ADT-030 is a potent, selective Phosphodiesterase 10A (PDE10A) inhibitor, inhibits enzymatic activity of recombinant PDE10 using cAMP and cGMP as substrates with IC50 of 0.95 uM and 1.15 uM respectively. |
| PC-25668 |
BRD9500
PDE3 modulator
|
BRD9500 is a potent, selective and orally active phosphodiesterases 3 (PDE3) inhibitor with IC50 of 10 and 27 nM for PDE3A and PDE3B, respectively. |
| PC-25123 |
ENPP1 inhibitor 31
ENPP1 inhibitor
|
ENPP1 inhibitor 31 is a highly potent ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1, PC-1) inhibitor with IC50 of 14.68 nM, effectively activates the STING pathway in cell lines. |
| PC-25102 |
Vizenpistat
ENPP1 inhibitor
|
Vizenpistat (SR-8541A) is a potent, selective ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) inhibitor. |
| PC-24673 |
ISM5939
ENPP1 inhibitor
|
ISM5939 is a potent and selective, orally bioavailable ENPP1 inhibitor with IC50 of 0.63 nM against the 2,3-cGAMP degradation and 9.28 nM against ATP hydrolysis. |
| PC-23567 |
ENPP1 inhibitor VIR3
ENPP1 inhibitor
|
VIR3 is a potent, orally bioavailable Enpp1 with IC50 of <0.75 nM for ENPP1 cGAMP hydrolysis activity inhibition in in vitro assays. |
| PC-23482 |
BC11-38
PDE11 inhibitor
|
BC11-38 is a potent and selective PDE11 inhibitor with IC50 of 0.28 uM, without acitivity against PDE1-10. |
