| Cat. No. |
Product Name |
Information |
| PC-22943 |
Ridinilazole
C. difficile inhibitor
|
Ridinilazole (SMT19969) is a narrow-spectrum, non-absorbable antimicrobial against Clostridium difficile with MIC of 0.125 to 0.5 ug/ml, MIC90 of 0.25 ug/mL, including ribotype 027 strains. |
| PC-22942 |
Ramoplanin
Antibiotic
|
Ramoplanin (A-16686) is a glycolipodepsipeptide antibiotic with MIC50 of 1.45 ug/mL against methicillin-resistant S. epidermidis (MRSE), shows activity against staphylococci, enterococci and C. difficile. |
| PC-22849 |
PBZ1587
GroES/GroEL inhibitor
|
PBZ1587 is a small-molecule inhibitor of the GroES/GroEL chaperone system with IC50 of 0.44 uM in MDH refolding assay, binds at the GroEL ring–ring interface (RRI). |
| PC-22848 |
PBZ1038
GroES/GroEL inhibitor
|
PBZ1038 is a small-molecule inhibitor of the GroES/GroEL chaperone system with IC50 of 1.2 uM against E. faecium GroES/GroEL refolding of malate dehydrogenase (MDH), binds at the GroEL ring–ring interface (RRI). |
| PC-22813 |
TST1N-224
S. aureus VraRC inhibitor
|
TST1N-224 is a potent inhibitor targeting the response regulator VraRC of S. aureus, inhibits the formation of the VraRC-DNA complex with IC50 of 60.2 uM, shows strong binding to VraRC (KD=23.4 uM), enhances the susceptibility of vancomycin-intermediate S. aureus (VISA) to both vancomycin and methicillin. |
| PC-22725 |
Kanamycin sulfate
Antibiotic
|
Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. |
| PC-22724 |
Kanamycin
Antibiotic
|
Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. |
| PC-22717 |
PQD-1
DHFR inhibitor
|
PQD-1 is a DHFR inhibitor with activity against Mycobacterium tuberculosis, PQD-1 synergizes with the dihydropteroate synthase (DHPS) inhibitor sulfamethoxazole (SMX). |
| PC-22699 |
C10-AMS
AasS inhibitor
|
C10-AMS is an acyl adenylate mimic and acyl-acyl carrier protein synthetase (AasS, acyl-ACP synthetase) inhibitor with Ki of 0.6 uM, inhibit the AasS-catalyzed loading of fatty acids onto acyl carrier protein (ACP). |
| PC-22691 |
Trypyricin 1
Antibacterial
|
Trypyricin 1 is a broad-spectrum antibacterial with MIC of 0.5 ug/mL for S. aureus MRSA252 (MRSA), membrane fluidizer, re-sensitizes methicillin-resistant MRSA to β-lactam antibiotics both in vitro and in mice. |
| PC-22663 |
Trimethoprim
DHFR inhibitor
|
Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase (DHFR) inhibitor, shows acitvity against a wide range of Gram-positive and Gram-negative aerobic bacteria. |
| PC-22624 |
AN2718
KPC-2 inhibitor
|
AN2718 is a small molecule inhibitor of the catalytic activity of the Klebsiella pneumoniae carbapenemase (KPC-2) enzyme with IC50 of 0.5 uM and ITC Kd of 86.3 nM, exhibit synergistic antimicrobial effect with Meropenem. |
