| Cat. No. |
Product Name |
Information |
| PC-49164 |
TXA709
FtsZ inhibitor
|
TXA709 is a prodrug of FtsZ-targeting benzamide compound (TXA707) with enhanced metabolic stability, demonstrates improved pharmacokinetic properties, and superior in vivo antistaphylococcal efficacy (both oral and intravenous) relative to previously identified prodrugs (TXY436 and TXY541) of PC190723. |
| PC-49163 |
TXA6101
FtsZ inhibitor
|
TXA6101 is an FtsZ-targeting compound with activity against MRSA isolates that express either G196S or G193D mutant FtsZ proteins, shows potent in vitro antibacterial activity against MRSA clinical isolate MPW020 with MIC of 0.125 ug/mL. |
| PC-49162 |
Sudapyridine
Antituberculosis
|
Sudapyridine (WX-081) is a potential new antituberculosis compound,excellent antimicrobial in vitro activity against both drug-susceptible and drug-resistant M. tuberculosis clinical isolates with MICs of 0.117 to 0.219 ug/mL. |
| PC-49157 |
JBD1
S. aureus biofilm inhibitor
|
JBD1 is a small molecule compound that strongly inhibits biofilm formation of S. aureus, including methicillin-resistant strains, induces biofilm inhibition and metabolic remodeling through respiratory activation. |
| PC-49113 |
MD-124
Antibiotic adjuvant
|
MD-124 is a potent antibiotic adjuvant against Gram-negative bacteria, sensitizes various Gram-negative bacterial species and strains, including multidrug resistant pathogens, toward existing antibiotics. |
| PC-49008 |
Fleroxacin
Antibiotic
|
Fleroxacin (AM833, Ro23-6240) is a broad-spectrum fluoroquinolone antibiotic, with activity against a variety of Gram-positive and Gram-negative bacteria with MIC90 values of 0.05 to 3.13 ug/mL. |
| PC-47040 |
Brilacidin tetrahydrochloride
Antiviral compound
|
Brilacidin (PMX-30063) is a synthetic, non-peptide, defensin-mimetic compound, exhibits broad-spectrum anti-microbial and anti-SARS-CoV-2 activities. |
| PC-47052 |
VU0026921
|
VU0026921 is a small molecule modulator of metal homeostasis in gram-positive pathogens, disrupts metal homeostasis in multiple Gram-positive bacteria, leading to increased reactive oxygen species and cell death. |
| PC-47041 |
D66
Antibacterial
|
D66 is a specific small molecule that disrupts S. Typhimurium membrane voltage without cell lysis, prevents S. Typhimurium survival in macrophages (IC50=6.0 uM) and inhibits bacterial growth under conditions that compromise the cell envelope. |
| PC-47012 |
PC190723
FtsZ inhibitor
|
PC190723 is a small molecule inhibitor of FtsZ with potent and selective anti-staphylococcal activity, inhibits FtsZ and prevents cell division. |
| PC-47011 |
DS01750413
FtsZ inhibitor
|
DS01750413 is a novel FtsZ inhibitor and new derivative of PC190723 (Cat. PC-47012), inhibits S. aureus FtsZ protein with IC50 of 2 mg/L, has an IC50 of 0.03 mg/L in cell elongation assay of B. subtilis. |
| PC-47010 |
TXY436
FtsZ inhibitor
|
TXY436 is an N-Mannich base derivative and FtsZ-directed prodrug of PC190723, TXY436 is effective against S. aureus can also target Gram-negative bacteria, such as Escherichia coli. |
