| Cat. No. |
Product Name |
Information |
| PC-42714 |
Pretomanid
Mtb inhibitor
|
Pretomanid (PA-824) is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid. |
| PC-26628 |
Chlorhexidine
Antibiotic
|
Chlorhexidine is an orally active cationic antimicrobial agent that targets microbial cell membranes, binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents, shows broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. |
| PC-26614 |
NSC 156565
Pycsar inhibitor
|
NSC 156565 is a specific small molecule inhibitor of bacterial Pycsar immune system, selectively suppresses the Pycsar-mediated antiphage defense by targeting the cytotoxic effects of the transmembrane effector PycTM. |
| PC-26607 |
VNRX-14079
N. gonorrhoeae PBP2 inhibitor
|
VNRX-14079 is a specific Neisseria gonorrhoeae penicillin-binding protein (PBP2) inhibitor with IC50 of 1.7 uM for N. gonorrhoeae FA19 strain, exhibits potent antibacterial activity against multidrug-resistant N. gonorrhoeae through high-affinity binding to the PBP2. |
| PC-26545 |
L-161240
LpxC inhibitor
|
L-161240 (L-161,240) is an antibacterial agent that inhibit lipid A biosynthesis, inhibits LpxC with IC50 of 26 nM and inhibition constant (Ki) of 50 nM, displays MIC of about 1 ug /mL against Escherichia coli. |
| PC-26544 |
BB-78485
LpxC inhibitor
|
BB-78485 is a potent inhibitor of LpxC with IC50 of 160 nM in E. coli LpxC assays, showspredominantly gram-negative activities with MIC of 2 ug/mL for E.coli D21. |
| PC-26543 |
PF-5081090
LpxC inhibitor
|
PF-5081090 (LpxC-4) is a highly potent LpxC inhibitor with IC50 of 1.1 nM (P. aeruginosa LpxC) and MIC90 of 1 ug/mL, inhibits lipid A biosynthesis and is synergistic with azithromycin, rifampin, or vancomycin for multidrug-resistant A. baumannii. |
| PC-26482 |
S-0636
PgQC inhibitor
|
S-0636 is a potent, reversible inhibitor of zinc-dependent glutaminyl cyclase (PgQC) with Ki of 14 nM, selectively inhibits the bacterial virulence of P. gingivalis. |
| PC-26452 |
Aztreonam
Antibiotic
|
Aztreonam is a monocyclic beta-lactam antibiotic. |
| PC-26394 |
CP-20-I
AgrC inhibitor
|
CP-20-I is a specific small molecule inhibitor of quorum sensing receptor AgrC in Staphylococcus aureus with IC50 of 180 nM in group-I S. aureus transcriptional reporter assays. |
| PC-26393 |
AgrC inhibitor CP-20
AgrC inhibitor
|
AgrC inhibitor CP-20 is a specific small molecule inhibitor of quorum sensing receptor AgrC in Staphylococcus aureus with IC50 of 0.93 uM in group-I S. aureus transcriptional reporter assays. |
| PC-26321 |
Cefidelbaz
Cephalosporin antibiotic
|
Cefidelbaz is a cephalosporin antibiotic with significant antibacterial activity against gram-negative bacterium with MICs of 0.125-0.5, 0.125-0.5 and 0.125-2 μg/mL for carbapenem-resistant Acinetobacter baumannii (CRAB), Klebsiella pneumoniae (CRE) and Pseudomonas aeruginosa (CRPA), respectively. |
