| Cat. No. |
Product Name |
Information |
| PC-45638 |
Ribocil-C
FMN riboswitch inhibitor
|
Ribocil-C is a highly selective inhibitor of the FMN riboswitch that controls expression of de novo riboflavin (Vitamin B2) biosynthesis in Escherichia coli. |
| PC-45926 |
Moxifloxacin
Antibiotic
|
Moxifloxacin is a fourth-generation synthetic fluoroquinolone, broad-spectrum antibacterial agent that is active against both Gram-positive and Gram-negative bacteria; inhibits DNA gyrase and topoisomerase IV. |
| PC-42665 |
Gatifloxacin
Bacterial DNA gyrase inhibitor
|
Gatifloxacin (PD 135432, AM1155) is a fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV. |
| PC-42048 |
Faropenem daloxate
Beta-lactam antibiotic
|
Faropenem daloxate (Faropenem medoxil) is a daloxate ester prodrug of Faropenem with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes, a beta-lactam antibiotic. |
| PC-42714 |
Pretomanid
Mtb inhibitor
|
Pretomanid (PA-824) is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid. |
| PC-26808 |
BRD1554
Mtb Pks13 inhibitor
|
BRD1554 is a selective inhibitor of Mycobacterium tuberculosis polyketide synthase 13 (Pks13). |
| PC-26790 |
Forazemin
Peptide deformylase inhibitor
|
Forazemin (BB-83698) is a potent, orally active peptide deformylase (PDF) inhibitor, shows antibacterial potency for gram-positive pathogens with MIC50 of 0.25 ug/mL and 0.06 ug/mL for Streptococcus pneumoniae and Moraxella catarrhalis. |
| PC-26780 |
Fluorothiazinone
T3SS inhibitor, Anti-virulence
|
Fluorothiazinone is a small molecule antivirulent compound that suppresses the formation of biofilms, inhibits the type III secretion system (T3SS) in Gram-negative bacteria. |
| PC-26720 |
KGDI-109
PgDPP7 inhibitor
|
KGDI-109 is the first substrate-mimetic dipeptide inhibitor of P. gingivalis dipeptidyl peptidase 7 (PgDPP7) with IC50 of 53.8 uM and Ki of 25.1 uM, exerts an inhibitory effect against P. gingivalis growth with MIC of 1.56 uM. |
| PC-26708 |
BDM91531
AcrB efflux pump inhibitor
|
BDM91531 is a potent AcrB efflux pump inhibitor, binds to the TMD of the L state and O state protomers of AcrB, exhibits potent potentiation of pyridomycin activity with EC90 of 0.24 uM. |
| PC-26671 |
Funobactam
β-lactamase inhibitor
|
Funobactam (XNW4107) is a novel β-lactamase inhibitor that possesses broad activity against serine-β-lactamases, displays in vitro activity against Ambler class A, C, and D β-lactamases. |
| PC-26668 |
GM47-1
MmpL3 inhibitor
|
GM47-1 is small molecule inhibitor targeting MmpL3 in Mycobacterium abscessus, has MIC50 of 1.6 uM and trigger a dose-dependent ATP increase with EC50 of 3 uM in Mycobacterium abscessus. |
