Cat. No. |
Product Name |
Information |
PC-38420 |
LpxC-IN-5
LpxC inhibitor
|
LpxC-IN-5 is a potent non-hydroxamate LpxC (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor with IC50 of 20 nM, shows antibacterial activity against E. coli ATCC25922, P. aeruginosa ATCC27853, K. pneumoniae ATCC13883 and P. aeruginosa 5567 with MIC of 16, 4, 64, and 4 ug/mL, respectively. |
PC-38406 |
QZN 34
PqsR inhibitor
|
QZN 34 is a small molecule pseudomonas aeruginosa PQS quorum-sensing system (PqsR) inhibitor with IC50 of 15 uM, kills planktonic Gram-positives (S. aureus, MIC 6.25 uM) but not Gram-negatives. |
PC-38403 |
Morponidazole
Antibiotic
|
Morponidazole is a nitroimidazoles antibiotic for bacterial infections. |
PC-38364 |
MCB-3681
Bactericidal antibiotic
|
MCB 3681 is a quinolonyl-oxazolidinone bactericidal antibiotic, has activity in vitro against Gram-positive bacteria. MCB3681 has a potent in vitro activity against C. difficile with MIC90 of 0.064 ug/ml. |
PC-38363 |
LFF-571
Bactericidal antibiotic
|
LFF571 is a semisynthetic thiopeptide and bactericidal antibiotic that interferes with bacterial protein synthesis by inhibition of elongation factor EF-Tu, LFF571 is potent in vitro activity against C.difficile strains with MIC90 of 0.25 ug/mL. |
PC-38362 |
MGB-BP-3
Bactericidal antibiotic
|
MGB-BP-3 is a potent bactericidal antibiotic with a completely novel mode of action, selectively binds to the minor grove of microbial DNA, has the potential for Clostridioides difficile infection (CDI). |
PC-38361 |
Ibezapolstat
DNA pol IIIC inhibitor
|
Ibezapolstat (ACX-362E) is a potent, selective, first-in-class DNA polymerase IIIC (DNA pol IIIC) inhibitor with IC50 of 51 nM (B. Subtilis pol IIIC), inhibits C. difficile efficiently (MIC50, 2 ug/mL). |
PC-73349 |
PTC-672
Ng RNR inhibitor
|
PTC-672 (PTC672) is a novel orally active inhibitor that exhibits a narrow spectrum of activity against Neisseria gonorrhoeae (N. gonorrhoeae, Ng) including MDR isolates (MIC, 0.05 to 0.4 ug/mL), directly inhibits class Ia ribonucleotide reductase (RNR). |
PC-73346 |
Xeruborbactam
Beta-lactamase inhibitor
|
Xeruborbactam (QPX7728) is an ultrabroad-spectrum beta-lactamase inhibitor, inhibits class A extended-spectrum beta-lactamases with IC50 of 1-3 nM, carbapenemases such as KPC (IC50, 2.9 nM), class C P99 (IC50, 22 nM). |
PC-73194 |
AX20017
M.tb PknG inhibitor
|
AX20017 is a highly selective inhibitor of Mycobacterium tuberculosis protein kinase G (PknG) with IC50 of 0.39 uM. |
PC-73144 |
Avibactam sodium
Beta-lactamase inhibitor
|
Avibactam sodium (NXL104) is a novel β-lactamase inhibitor with a non-lactam structural scaffold, irreversibly inhibits lactamase from Mycobacterium tuberculosis. |
PC-73118 |
Burkfloxacin
Burkholderia inhibitor
|
Burkfloxacin (BFX) is a fluoroquinolone analog that potently inhibits growth of intracellular Burkholderia. |