Bacterial compound (inhibitors, antagonists)-ProbeChem.com

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Bacteria constitute a large domain of prokaryoticmicroorganisms. Antibiotics (also called antibacterials) are a type of antimicrobial drug used in the treatment and prevention of bacterial infections, a limited number of antibiotics also possess antiprotozoal activity. Together with vaccination, antibiotics have led to the near eradication of diseases such as tuberculosis in the developed world. However, their effectiveness and easy access have also led to their overuse, prompting bacteria to develop resistance.

A bactericidal activity of antibacterials may depend on the bacterial growth phase, and it often requires ongoing metabolic activity and division of bacterial cells. In vitro characterization of antibacterial activity commonly includes the determination of the minimum inhibitory concentration and minimum bactericidal concentration of an antibacterial. To predict clinical outcome, the antimicrobial activity of an antibacterial is usually combined with its pharmacokinetic profile, and several pharmacological parameters are used as markers of drug efficacy.

Cat. No.	Product Name	Information
PC-42061	Tubercidin	An antibiotic and adenosine analog isolated from the bacterium Streptomyces tubercidicus with potential antineoplastic activity.
PC-45392	Framycetin	An aminoglycoside antibiotic.
PC-45349	Apramycin	An aminoglycoside antibiotic used in veterinary medicine..
PC-45352	G-418 disulfate	An aminoglycoside antibiotic similar in structure to gentamicin B1.
PC-45269	Cefditoren pivoxil	A third-generation cephalosporin antibiotic that has been used to treat bacterial infections of the skin and respiratory tract, including bronchitis, pneumonia, and tonsillitis..
PC-45234	Minocycline hydrochloride	A tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects..
PC-45351	Demeclocycline hydrochloride	A tetracycline antibiotic that acts by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA which impairs protein synthesis by bacteria.
PC-42273	Antibiotic-5d	A synthetic antimicrobial compound that antibacterial activity in vitro against various Gram-positive and Gram-negative bacteria, fungi and yeast..
PC-45284	Sancycline	A semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin..
PC-45148	Rifabutin	A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. .
PC-45276	Garenoxacin	A quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections..
PC-42189	Nanchangmycin	A polyether ionophore antibiotic isolated from Streptomyces nanchangensis NS3226 that shows antibacterial and antiviral properties.

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