| Cat. No. |
Product Name |
Information |
| PC-42048 |
Faropenem daloxate
Beta-lactam antibiotic
|
Faropenem daloxate (Faropenem medoxil) is a daloxate ester prodrug of Faropenem with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes, a beta-lactam antibiotic. |
| PC-42714 |
Pretomanid
Mtb inhibitor
|
Pretomanid (PA-824) is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid. |
| PC-28806 |
Rifapentine
Antibiotic, Bacterial RNA polymerase inhibitor
|
Rifapentine is a semisynthetic derivative antibiotic of rifampicin, inhibits DNA-dependent RNA polymerase in susceptible strains of M. tuberculosis, leading to a suppression of RNA synthesis and cell death, shwos potent antibacterial activity against TB and other mycobacterial species. |
| PC-28676 |
AX-35
QcrB inhibitor, Cyt bc1 inhibitor
|
AX-35 (GW861072X) is a potent M. tuberculosis inhibitor targeting the QcrB subunit of the cytochrome bc1 oxidase, has MIC of 0.05 ug/ml against M. tuberculosis H37Rv and 0.1 ug/mL for M. tuberculosis H37Rv-infected THP-1 macrophages. |
| PC-28666 |
MreB inhibitor A22 hydrochloride
MreB inhibitor
|
MreB inhibitor A22 hydrochloride is a specific small molecule inhibitor of bacterial actin MreB, binds directly to the MreB filament, altering its structure and causing a morphological change of the cell, leading to cell death. |
| PC-28665 |
MreB inhibitor A22
MreB inhibitor
|
MreB inhibitor A22 is a specific small molecule inhibitor of bacterial actin MreB, binds directly to the MreB filament, altering its structure and causing a morphological change of the cell, leading to cell death. |
| PC-28637 |
LasR inhibitor 2g
LasR inhibitor
|
LasR inhibitor 2g is a potent, small molecule inhibitor of P. aeruginosa QS hierarchy LasR, demonstrated exceptional biofilm inhibition with IC50 of 0.14 uM, binds LasR with high affinity (KD=38.97 uM), suppresses LasR-regulated virulence pathways, reduces pyocyanin production and bacterial motility, shows synergistic antibiotic enhancement activity. |
| PC-28636 |
LasR-IN-6
LasR inhibitor
|
LasR-IN-6 (Cpmpound 7d) is a potent quorum sensing (QS) system LasR inhibitor with IC50 of 0.261 uM, has MIC of 62.5 uM against P. aeruginosa PAO1, significantly suppressed key virulence factors, including protease production, biofilm formation, and motility phenotypes in P. aeruginosa. |
| PC-28635 |
LasR-IN-5
LasR inhibitor
|
LasR-IN-5 (Cpmpound 3c) is a potent quorum sensing (QS) system LasR inhibitor with IC50 of 1.37 uM, inhibits biofilm formation, pyocyanin, and rhamnolipids production in Pseudomonas aeruginosa. |
| PC-28634 |
LasR-IN-4
LasR inhibitor
|
LasR-IN-4 (Cpmpound 3d) is a potent quorum sensing (QS) system LasR inhibitor, inhibits QS by modulating the expression of virulence factors or by targeting LasR, inhibits biofilm formation, pyocyanin, and rhamnolipids production in Pseudomonas aeruginosa. |
| PC-28633 |
LasR-IN-3
LasR inhibitor
|
LasR-IN-3 (Cpmpound 7f) is a potent quorum sensing (QS) system LasR inhibitor, inhibits QS by modulating the expression of virulence factors or by targeting LasR, inhibits biofilm formation, pyocyanin, and rhamnolipids production in Pseudomonas aeruginosa. |
| PC-28632 |
XDS-23
LasI/LasR inhibitor
|
XDS-23 is a selective biofilm inhibitor with IC50 of 1.26 uM for inhibiting biofilm in P. aeruginosa PAO1, inhibits LasI/LasR System (las) and Pseudomonas Quinolone Signal System (pqs), suppresses the production of key virulence factors including elastase, pyocyanin, and extracellular polysaccharides, exhibits synergistic antibacterial activity and can enhance the efficacy of multiple antibiotics in both in vitro and in vivo. |
