Cat. No. |
Product Name |
Information |
PC-24339 |
Astrazeneca Arylaminotriazine
DNA gyrase inhibitor
|
Astrazeneca Arylaminotriazine is a promising DNA gyrase inhibitor with profound antibacterial activity. |
PC-24338 |
10-F05
FabH/MiaA inhibitor
|
10-F05 is a covalent small molecule inhibitor of bacterial β-ketoacyl-acyl carrier protein synthase III (FabH) and MiaA tRNA prenyltransferase, demonstrates broad-spectrum antibacterial effectiveness (MIC=2.5 uM, S. flexneri). |
PC-24315 |
Lariocidin
Antibiotic
|
Lariocidin (LAR) is a novel ribosome-targeting lasso peptide antibiotic inhibit bacterial growth by binding to the ribosome and interfering with protein synthesis. |
PC-24305 |
P2-56-3
Rifampin potentiator
|
P2-56-3 is small-molecule sensitizer of antibiotic-resistant gram-negative ESKAPE pathogens, potentiates rifampin against antibiotic-resistant strains of Acinetobacter baumannii and Klebsiella pneumoniae, disrupts the outer membrane of A. baumannii. |
PC-24304 |
Rifampin
Antibiotic
|
Rifampin (Rifampicin) is a potent and broad spectrum antibiotic against bacterial pathogens, also has anti-influenza virus and anti-orthopoxvirus activities. |
PC-24301 |
Fosfomycin sodium
Antibiotic
|
Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis, shows a wide range antibacterial activity, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. |
PC-24300 |
Fosfomycin calcium
Antibiotic
|
Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis, shows a wide range antibacterial activity, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. |
PC-24236 |
FBX-1991
H. pylori FabX inhibitor
|
FBX-1991 is a potent, specific small molecule inhibitor of Helicobacter pylori (H. pylori) dehydrogenase/isomerase FabX with IC50 of 0.158 uM, shows potent antibacterial activity against strain BHKS211 with MIC of 16 ug/mL. |
PC-24201 |
ChlaDUB1 inhibitor 27a
ChlaDUB1 inhibitor
|
ChlaDUB1 inhibitor 27a is a specific covalent inhibitor of bacterial chlamydial deubiquitinase 1 (ChlaDUB1) with IC50 of 0.97 uM, inhibits chlamydial growth with IC50 of 25.6 ug/mL. |
PC-24195 |
Xeruborbactam disodium
Beta-lactamase inhibitor
|
Xeruborbactam (QPX7728) disodium is an ultrabroad-spectrum beta-lactamase inhibitor, inhibits class A extended-spectrum beta-lactamases with IC50 of 1-3 nM, carbapenemases such as KPC (IC50, 2.9 nM), class C P99 (IC50, 22 nM). |
PC-24194 |
Xeruborbactam isoboxil
Beta-lactamase inhibitor
|
Xeruborbactam isoboxil is the prodrug of xeruborbactam, an ultrabroad-spectrum beta-lactamase inhibitor, inhibits class A extended-spectrum beta-lactamases with IC50 of 1-3 nM, carbapenemases such as KPC (IC50, 2.9 nM), class C P99 (IC50, 22 nM). |
PC-24024 |
MraY inhibitor 12a
MraY inhibitor
|
MraY inhibitor 12a is a first-in-class, non-nucleoside inhibitor of bacterial enzyme MraY with IC50 of 25 uM, exhibits broad-spectrum antibacterial activity. |