| Cat. No. |
Product Name |
Information |
| PC-27136 |
SmcR inhibitor PTSP
SmcR inhibitor
|
PTSP is a specific and potent inhibitor of Vibrio LuxR/HapR proteins and LuxR homolog SmcR in Vibrio vulnificus, inhibits quorum sensing in multiple strains of V. vulnificus, V. parahaemolyticus, and V. campbellii. |
| PC-27134 |
ZN148
Metallo-β-lactamase inhibitor
|
ZN148 (APC148) is a specific, irreversible, zinc-chelating metallo-β-lactamase (MBL) inhibitor with broad activity against Ambler class B enzymes, including NDM, VIM, and IMP, restores the in vitro and in vivo activity of meropenem against multidrug-resistant MBL-producing Enterobacterales. |
| PC-27116 |
Cap5-IN-1
Bacterial Cap5 inhibitor
|
Cap5-IN-1 is a competitive, cellulo active inhibitor of bacterial cyclic oligonucleotide-based anti-phage signaling system (CBASS) effector nuclease Cap5, effectively blocks phage defenses in bacteria. |
| PC-27101 |
MP20
N. gonorrhoeae inhibitor
|
MP20 is a small molecule antibiotic effective against Neisseria gonorrhoeae with MIC of 4 ug/mL for N. gonorrhoeae ATCC 49226, shows in vitro efficacy against multidrug-resistant N. gonorrhoeae strains |
| PC-27035 |
Linezolid
Antibacterial
|
Linezolid (PNU-100766) is an oxazolidone antibiotic for staphylococcal and streptococcal infections, also has certain activity against gram-negative bacteria and anaerobes, also is a selective inhibitor of JAK2 V617F mutation but not with wild-type JAK2 protein. |
| PC-26865 |
AIP-II
AgrC inhibitor
|
AIP-II is a peptidomimetic inhibitor of staphylococcus aureus AgrC quorum sensing receptors, inhibits AgrC-III in methicillin-resistant type III Staphylococcus aureus strain AH1747 with IC50 of 0.532 nM, binds to the AgrC-II receptor and regulates virulence gene expression in Staphylococcus aureus. |
| PC-26828 |
MRL-494 hydrochloride
BamA inhibitor
|
MRL-494 hydrochloride (MRL494) is an antimicrobial small molecule that inhibits assembly of outer membrane proteins (OMPs) by the β-barrel assembly machine (BAM complex), inhibits the insertion of OMPs into the OM by targeting BamA. |
| PC-26808 |
BRD1554
Mtb Pks13 inhibitor
|
BRD1554 is a selective inhibitor of Mycobacterium tuberculosis polyketide synthase 13 (Pks13). |
| PC-26780 |
Fluorothiazinone
T3SS inhibitor, Anti-virulence
|
Fluorothiazinone is a small molecule antivirulent compound that suppresses the formation of biofilms, inhibits the type III secretion system (T3SS) in Gram-negative bacteria. |
| PC-26720 |
KGDI-109
PgDPP7 inhibitor
|
KGDI-109 is the first substrate-mimetic dipeptide inhibitor of P. gingivalis dipeptidyl peptidase 7 (PgDPP7) with IC50 of 53.8 uM and Ki of 25.1 uM, exerts an inhibitory effect against P. gingivalis growth with MIC of 1.56 uM. |
| PC-26708 |
BDM91531
AcrB efflux pump inhibitor
|
BDM91531 is a potent AcrB efflux pump inhibitor, binds to the TMD of the L state and O state protomers of AcrB, exhibits potent potentiation of pyridomycin activity with EC90 of 0.24 uM. |
| PC-26671 |
Funobactam
β-lactamase inhibitor
|
Funobactam (XNW4107) is a novel β-lactamase inhibitor that possesses broad activity against serine-β-lactamases, displays in vitro activity against Ambler class A, C, and D β-lactamases. |
