| Cat. No. |
Product Name |
Information |
| PC-45367 |
Fidaxomicin
Antibiotic
|
Fidaxomicin (OPT-80, PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug and RNA polymerase inhibitor, shows potent anti-Clostridium difficile activity with MIC90 of 0.12 ug/mL. |
| PC-42715 |
Delamanid
|
Delamanid (OPC-67683) is a mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis, including MDR-TB. |
| PC-45263 |
Azathramycin
Antibiotic
|
Azathramycin is a macrolide antibiotic that effectively inhibits tumor angiogenesis by suppressing VEGFR2-mediated signaling pathways in lung cancer. |
| PC-45638 |
Ribocil-C
FMN riboswitch inhibitor
|
Ribocil-C is a highly selective inhibitor of the FMN riboswitch that controls expression of de novo riboflavin (Vitamin B2) biosynthesis in Escherichia coli. |
| PC-42665 |
Gatifloxacin
Bacterial DNA gyrase inhibitor
|
Gatifloxacin (PD 135432, AM1155) is a fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV. |
| PC-42048 |
Faropenem daloxate
Beta-lactam antibiotic
|
Faropenem daloxate (Faropenem medoxil) is a daloxate ester prodrug of Faropenem with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes, a beta-lactam antibiotic. |
| PC-42714 |
PA-824
Antibiotic
|
Pretomanid (PA-824) is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid. |
| PC-24024 |
MraY inhibitor 12a
MraY inhibitor
|
MraY inhibitor 12a is a first-in-class, non-nucleoside inhibitor of bacterial enzyme MraY with IC50 of 25 uM, exhibits broad-spectrum antibacterial activity. |
| PC-23990 |
Enoxacin
DNA Gyrase inhibitor
|
Enoxacin (Enoxacin sesquihydrate) is a fluoroquinolone antibiotic, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml).
Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs.
Enoxacin shows potent activities against gram-positive and -negative bacteria.
Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-bi |
| PC-23989 |
Enoxacin hydrate
DNA Gyrase inhibitor
|
Enoxacin hydrate (Enoxacin sesquihydrate) is a fluoroquinolone antibiotic, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml). |
| PC-23925 |
V-161
EhV-ATPase inhibitor
|
V-161 is a potent, specific E. hirae Na+-transporting V-ATPase (EhV-ATPase) inhibitor with IC50 of 144 nM, blocks the function of Na+-transporting V-ATPase and preferentially inhibits the growth of enterococci. |
| PC-23867 |
BRD1401
OprH-LPS inhibitor
|
BRD1401 is a P. aeruginosa-specific inhibitor targeting outer membrane protein OprH-LPS interaction, increases membrane fluidity. |
