Bacterial compound (inhibitors, antagonists)-ProbeChem.com

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Bacteria constitute a large domain of prokaryoticmicroorganisms. Antibiotics (also called antibacterials) are a type of antimicrobial drug used in the treatment and prevention of bacterial infections, a limited number of antibiotics also possess antiprotozoal activity. Together with vaccination, antibiotics have led to the near eradication of diseases such as tuberculosis in the developed world. However, their effectiveness and easy access have also led to their overuse, prompting bacteria to develop resistance.

A bactericidal activity of antibacterials may depend on the bacterial growth phase, and it often requires ongoing metabolic activity and division of bacterial cells. In vitro characterization of antibacterial activity commonly includes the determination of the minimum inhibitory concentration and minimum bactericidal concentration of an antibacterial. To predict clinical outcome, the antimicrobial activity of an antibacterial is usually combined with its pharmacokinetic profile, and several pharmacological parameters are used as markers of drug efficacy.

Cat. No.	Product Name	Information
PC-45354	Capreomycin sulfate	A peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis. .
PC-45426	MUT-056399	A novel, highly potent inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli.
PC-45327	Meptyldinocap	A novel powdery mildew (Erysiphe necator) fungicide that shows protectant and post-infective activities. .
PC-45967	I-2906	A novel isocitrate lyase (ICL) inhibitor that displays showed excellent anti-Mycobacterium tuberculosisl activities and low cytotoxicity.
PC-45378	Solithromycin	A novel fluoroketolide with lower MICs than those of telithromycin and macrolides.
PC-45330	Bethoxazin	A new broad spectrum industrial microbicide with applications in material and coating preservation. .
PC-45307	Azithromycin	A macrolide antibiotic used for the treatment of a number of bacterial infections.
PC-45926	Moxifloxacin	A fourth-generation synthetic fluoroquinolone, broad-spectrum antibacterial agent that is active against both Gram-positive and Gram-negative bacteria.
PC-45925	Moxifloxacin hydrochloride	A fourth-generation synthetic fluoroquinolone, broad-spectrum antibacterial agent that is active against both Gram-positive and Gram-negative bacteria.
PC-42667	Gatifloxacin mesylate	A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.
PC-42666	Gatifloxacin hydrochloride	A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.
PC-45150	Besifloxacin hydrochloride	A fourth-generation fluoroquinolone antibiotic that exhibits a broad spectrum in vitro activity against a wide range of Gram-positive and Gram-negative ocular pathogens..

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