| Cat. No. |
Product Name |
Information |
| PC-27561 |
MBX1641
Type III secretion inhibitor, YspD ligand
|
MBX1641 (MBX-1641) is a small-molecule inhibitor of bacterial type III secretion (TTS, T3SS), not only bind effectively with YspD, but also bind to the functionally important domains of YspD and might lead to the functional inactivation of YspD, inhibits TIIISS effector protein ExoS in P. aeruginosa. |
| PC-27472 |
Luxafimloc
FimH inhibitor
|
Luxafimloc is a small molecule Escherichia coli fimbrial (FimH) adhesin inhibitor. |
| PC-27434 |
Saeamid-1
MRSA SaeS inhibitor
|
Saeamid-1 is a potential antivirulence compound and SaeS-targeting antagonist against methicillin-resistant Staphylococcus aureus (MRSA), reduces hemolytic activity and biofilm biomass while having only limited effects on MRSA growth. |
| PC-27401 |
Geneticin
Antibiotic
|
Geneticin (G418, Antibiotic G-418) is an aminoglycoside antibiotic with a structure similar to gentamicin, is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis. |
| PC-27400 |
Pefloxacin
Antibiotic
|
Pefloxacin is a fluoroquinolone antibiotic used for various bacterial infections, inhibits Plasmodium falciparum in vitro, inhibit eucaryotic DNA polymerase alpha and beta, terminal deoxynucleotidyl transferase. |
| PC-27399 |
Amifloxacin
Antibiotic
|
Amifloxacin (WIN 49375) is an quinolone carboxylic acid antibacterial agent with MIC of 4 ug/mL against aminoglycoside-resistant Pseudomonas aeruginosa, shows broad activity for gentamicin-resistant gram-negative bacilli. |
| PC-27374 |
OSSL-632214
Mtb TrxB2 inhibitor
|
OSSL-632214 (OSSL_632214) is a potent anti-Mtb compound with MIC of 3.13-6.25 μg/mL in vitro, possibly acts by targeting Thioredoxin reductase (TrxB2, Rv3913) and inducing lipid peroxidation in Mtb. |
| PC-27279 |
Mtb IMPDH2-IN-2
Mtb IMPDH2 inhibitor
|
MtbIMPDH2-IN-2 is a potent, selective Mycobacterium tuberculosis (Mtb) inosine 5'-monophosphate dehydrogenase 2 (MtbIMPDH2) inhibitor with IC50 of 12 nM, and MIC of 12 uM for Mtb, blocks the biosynthesis of guanine nucleotides. |
| PC-27208 |
Kalamycin
METTL1 inhibitor, Antibiotic
|
Kalamycin (Kalafungin, U-19718, NSC137443) is an antibiotic, antimicrobial agent and β-lactamase inhibitor from marine Streptomyces, also is a potent inhibitor of METTL1 methyltransferase activity with IC50 of 8.9 uM, demonstrates potent antileukemia efficacy, also shows inhibitory activities against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria. |
| PC-27160 |
UCP1173
DHFR inhibitor, Antifolate
|
UCP1173 is an antibacterial dihydrofolate reductase (DHFR) inhibitor with IC50 of 14 nM, 190 nM, 270 nM and 91 nM for S. aureus DfrB (wt SaDHFR), DfrG, DfrA and DfrK, potent activity against MRSA strains possessing dfrA with MIC values of 1.25 and 2.5 ug/mL. |
| PC-27136 |
SmcR inhibitor PTSP
SmcR inhibitor
|
PTSP is a specific and potent inhibitor of Vibrio LuxR/HapR proteins and LuxR homolog SmcR in Vibrio vulnificus, inhibits quorum sensing in multiple strains of V. vulnificus, V. parahaemolyticus, and V. campbellii. |
| PC-27134 |
ZN148
Metallo-β-lactamase inhibitor
|
ZN148 (APC148) is a specific, irreversible, zinc-chelating metallo-β-lactamase (MBL) inhibitor with broad activity against Ambler class B enzymes, including NDM, VIM, and IMP, restores the in vitro and in vivo activity of meropenem against multidrug-resistant MBL-producing Enterobacterales. |
