| Cat. No. |
Product Name |
Information |
| PC-24338 |
10-F05
FabH/MiaA inhibitor
|
10-F05 is a covalent small molecule inhibitor of bacterial β-ketoacyl-acyl carrier protein synthase III (FabH) and MiaA tRNA prenyltransferase, demonstrates broad-spectrum antibacterial effectiveness (MIC=2.5 uM, S. flexneri). |
| PC-24315 |
Lariocidin
Antibiotic
|
Lariocidin (LAR) is a novel ribosome-targeting lasso peptide antibiotic inhibit bacterial growth by binding to the ribosome and interfering with protein synthesis. |
| PC-24305 |
P2-56-3
Rifampin potentiator
|
P2-56-3 is small-molecule sensitizer of antibiotic-resistant gram-negative ESKAPE pathogens, potentiates rifampin against antibiotic-resistant strains of Acinetobacter baumannii and Klebsiella pneumoniae, disrupts the outer membrane of A. baumannii. |
| PC-24304 |
Rifampin
Antibiotic
|
Rifampin (Rifampicin) is a potent and broad spectrum antibiotic against bacterial pathogens, also has anti-influenza virus and anti-orthopoxvirus activities. |
| PC-24301 |
Fosfomycin sodium
Antibiotic
|
Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis, shows a wide range antibacterial activity, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. |
| PC-24300 |
Fosfomycin calcium
Antibiotic
|
Fosfomycin (MK-0955) calcium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis, shows a wide range antibacterial activity, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. |
| PC-24201 |
ChlaDUB1 inhibitor 27a
ChlaDUB1 inhibitor
|
ChlaDUB1 inhibitor 27a is a specific covalent inhibitor of bacterial chlamydial deubiquitinase 1 (ChlaDUB1) with IC50 of 0.97 uM, inhibits chlamydial growth with IC50 of 25.6 ug/mL. |
| PC-24194 |
Xeruborbactam isoboxil
Beta-lactamase inhibitor
|
Xeruborbactam isoboxil is the prodrug of xeruborbactam, an ultrabroad-spectrum beta-lactamase inhibitor, inhibits class A extended-spectrum beta-lactamases with IC50 of 1-3 nM, carbapenemases such as KPC (IC50, 2.9 nM), class C P99 (IC50, 22 nM). |
| PC-24024 |
MraY inhibitor 12a
MraY inhibitor
|
MraY inhibitor 12a is a first-in-class, non-nucleoside inhibitor of bacterial enzyme MraY with IC50 of 25 uM, exhibits broad-spectrum antibacterial activity. |
| PC-23990 |
Enoxacin
DNA Gyrase inhibitor
|
Enoxacin (Enoxacin sesquihydrate) is a fluoroquinolone antibiotic, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml).
Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs.
Enoxacin shows potent activities against gram-positive and -negative bacteria.
Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-bi |
| PC-23989 |
Enoxacin hydrate
DNA Gyrase inhibitor
|
Enoxacin hydrate (Enoxacin sesquihydrate) is a fluoroquinolone antibiotic, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml). |
| PC-23925 |
V-161
EhV-ATPase inhibitor
|
V-161 is a potent, specific E. hirae Na+-transporting V-ATPase (EhV-ATPase) inhibitor with IC50 of 144 nM, blocks the function of Na+-transporting V-ATPase and preferentially inhibits the growth of enterococci. |
