| Cat. No. |
Product Name |
Information |
| PC-27796 |
Magainin II
Antibacterial
|
Magainin II (Magainin 2) is an antimicrobial peptide isolated from the skin of Xenopus laevis,exhibits antibiotic activity, inhibits growth of numerous species of bacteria and fungi and induce osmotic lysis of protozoa. |
| PC-27795 |
Magainin I
Antibacterial
|
Magainin I (Magainin 1) is an antimicrobial peptide isolated from the skin of Xenopus laevis, exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria. |
| PC-27794 |
Pexiganan acetate
Antibacterial
|
Pexiganan acetate (MSI-78) is an analog of magainin and orally active antimicrobial peptide with broad-spectrum bactericidal activity, disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis, has MIC90 of ≤ 32 ug/mL for clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria. |
| PC-27793 |
Pexiganan
Antibacterial
|
Pexiganan (MSI-78) is an analog of magainin and orally active antimicrobial peptide with broad-spectrum bactericidal activity, disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis, has MIC90 of ≤ 32 ug/mL for clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria. |
| PC-27726 |
ACHN-975 TFA
LpxC inhibitor
|
ACHN-975 TFA (ACHN975) is a potent bacterial LpxC inhibitor with IC50 of 0.68 nM (P. aeruginosa LpxC). |
| PC-27677 |
Clofoctol
Antibiotic, UPR activator
|
Clofoctol is an antimicrobial agent via inhibition of the cell wall synthesis, also is an activator of unfolded protein response (UPR) pathways, inhibits prostate cancer cell proliferation. |
| PC-27654 |
Cilastatin sodium
DPEP1 inhibitor
|
Cilastatin sodium (MK-0791) is a reversible, competitive renal dehydropeptidase I (DPEP1) inhibitor with IC50 of 0.1 uM, also inhibits bacterial metallob-lactamase enzyme CphA, suppresses the invasion and metastasis of DPEP1-expressing cells. |
| PC-27653 |
Cilastatin
DPEP1 inhibitor
|
Cilastatin (MK-0791) is a reversible, competitive renal dehydropeptidase I (DPEP1) inhibitor with IC50 of 0.1 uM, also inhibits bacterial metallob-lactamase enzyme CphA, suppresses the invasion and metastasis of DPEP1-expressing cells. |
| PC-27588 |
Ceftazidime
β-lactam antibiotic
|
Ceftazidime (Fortaz, GR20263) is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against resistant bacteria such as Pseudomonas aeruginosa, a β-lactam antibiotic. |
| PC-27563 |
TTS29
Type III secretion inhibitor
|
TTS29 is a small molecule inhibitor of S. typhimurium type III secretion system (T3SS), disrupts the needle assembly of Yersinia spp., P. aeruginosa and Francisella novicida, block the secretion and virulence functions of a wide array of animal and plant Gram-negative bacterial pathogens, such as Y. spp., P. aeruginosa and Francisella novicida. |
| PC-27562 |
INP0010
Type III secretion inhibitor
|
INP0010 is a small-molecular inhibitor of bacterial virulence factor, inhibits type III secretion system (T3SS), prevents virulence factor-mediated replication of S. Typhimurium in macrophage-like RAW264.7 cells. |
| PC-27561 |
MBX1641
Type III secretion inhibitor, YspD ligand
|
MBX1641 (MBX-1641) is a small-molecule inhibitor of bacterial type III secretion (TTS, T3SS), not only bind effectively with YspD, but also bind to the functionally important domains of YspD and might lead to the functional inactivation of YspD, inhibits TIIISS effector protein ExoS in P. aeruginosa. |
