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Request The Product List ofBacterial Bacterial

Bacteria constitute a large domain of prokaryoticmicroorganisms. Antibiotics (also called antibacterials) are a type of antimicrobial drug used in the treatment and prevention of bacterial infections, a limited number of antibiotics also possess antiprotozoal activity. Together with vaccination, antibiotics have led to the near eradication of diseases such as tuberculosis in the developed world. However, their effectiveness and easy access have also led to their overuse, prompting bacteria to develop resistance.

A bactericidal activity of antibacterials may depend on the bacterial growth phase, and it often requires ongoing metabolic activity and division of bacterial cells. In vitro characterization of antibacterial activity commonly includes the determination of the minimum inhibitory concentration and minimum bactericidal concentration of an antibacterial. To predict clinical outcome, the antimicrobial activity of an antibacterial is usually combined with its pharmacokinetic profile, and several pharmacological parameters are used as markers of drug efficacy.

 
 

Cat. No. Product Name Information
PC-45713

N-Acetyl-Calicheamicin

N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic.
PC-45750

Vaborbactam

serine β-lactamase inhibitor

Vaborbactam (RPX-7009) is a serine β-lactamase inhibitor that notably restores the activity of carbapenems against KPC-producing strains.
PC-45070

Relebactam

Relebactam (MK-7655) is a novel β-lactamase inhibitor that inhibited both class A and C β-lactamases in vitro.
PC-45372

Dalbavancin

Antibiotic

Dalbavancin (MDL-63397, BI-397) is a novel second-generation lipoglycopeptide antibiotic with MIC90 values of 0.06 μg/mL and 0.25 μg/mL for Staphylococcus aureus and Bacillus anthracis, respectively.
PC-42302

Q203

A novel potent anti-tuberculosis agent targeting cytochrome b subunit qcrB, inhibits M. tuberculosis H37Rv with MIC50 of of 2.7 nM.
PC-45367

Fidaxomicin

Fidaxomicin(OPT-80; PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug, selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria.
PC-42715

Delamanid

Delamanid (OPC-67683) is a mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis, including MDR-TB.
PC-45638

Ribocil-C

FMN riboswitch inhibitor

Ribocil-C is a highly selective inhibitor of the FMN riboswitch that controls expression of de novo riboflavin (Vitamin B2) biosynthesis in Escherichia coli.
PC-42714

PA-824

Antibiotic

Pretomanid (PA-824) is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid.
PC-21955

S. aureus antibiotic 2

Antibiotic

S. aureus antibiotic 2 is a novel antibiotic exhibiting antibiotic activity against Staphylococcus aureus (MIC=4 ug/mL, MRSA USA300), can overcome common resistance determinants and antibiotic tolerance in Gram-positive bacteria.
PC-21954

S. aureus antibiotic 1

Antibiotic

S. aureus antibiotic 1 is a novel antibiotic exhibiting antibiotic activity against Staphylococcus aureus (MIC=4 ug/mL, MRSA USA300), can overcome common resistance determinants and antibiotic tolerance in Gram-positive bacteria.
PC-21953

Zosurabalpin

Antibiotic

Zosurabalpin is a small-molecule, tethered macrocyclic peptide antibiotic targeting the lipopolysaccharide transporter, has MIC of 0.06 ug/mL A. baumannii ATCC 17978.

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