| Cat. No. |
Product Name |
Information |
| PC-23990 |
Enoxacin
DNA Gyrase inhibitor
|
Enoxacin (Enoxacin sesquihydrate) is a fluoroquinolone antibiotic, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml).
Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs.
Enoxacin shows potent activities against gram-positive and -negative bacteria.
Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-bi |
| PC-23989 |
Enoxacin hydrate
DNA Gyrase inhibitor
|
Enoxacin hydrate (Enoxacin sesquihydrate) is a fluoroquinolone antibiotic, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml). |
| PC-23925 |
V-161
EhV-ATPase inhibitor
|
V-161 is a potent, specific E. hirae Na+-transporting V-ATPase (EhV-ATPase) inhibitor with IC50 of 144 nM, blocks the function of Na+-transporting V-ATPase and preferentially inhibits the growth of enterococci. |
| PC-23867 |
BRD1401
OprH-LPS inhibitor
|
BRD1401 is a P. aeruginosa-specific inhibitor targeting outer membrane protein OprH-LPS interaction, increases membrane fluidity. |
| PC-23837 |
Mycobactin
1400-46-0
|
Mycobactin (Mycobactin M) is a conditionally essential molecule expressed by mycobacteria in iron-stress conditions. |
| PC-23818 |
Bio-AMS
Biotin protein ligase inhibitor
|
Bio-AMS is a potent bacterial biotin protein ligase (BPL) inhibitor, possesses selective activity against Mycobacterium tuberculosis (Mtb) and inhibits fatty acid and lipid biosynthesis. |
| PC-23766 |
MtbFadD32 inhibitor M1
Mtb FadD32 inhibitor
|
MtbFadD32 inhibitor M1 is a small molecule inhibitor of Mycobacterium tuberculosis fatty acyl-AMP ligase FadD32 and FadD28, shows specific antitubercular activity with IC50 of 4.8 ug/mL, binds and inhibits the FAAL activity of MtbFadD32 and MtbFadD28 enzymes. |
| PC-23757 |
STK848198
FtsH inhibitor
|
STK848198 is a small molecule antimicrobial compound with MIC of 2 ug/mL against S. aureus by targeting ATP‐binding protein FtsH, inhibits methicillin‐sensitive S. aureus, MSRA, VAN intermediate S. aureus (VISA), and DAP‐resistant strains with MIC ranged from 0.5 to 8 ug/mL. |
| PC-23656 |
Evybactin
M.tb DNA gyrase inhibitor
|
Evybactin is a potent and selective antibiotic acting against M. tuberculosis (MIC=0.25 ug/mL) targeting DNA gyrase. |
| PC-23591 |
Miltefosine
58066-85-6
|
Miltefosine is a phosphatidylcholine analog with anti-leishmanial activity, inhibits PI3K/Akt activity, shows broad spectrum antimicrobial, anti-leishmanial and anticoronaviral activity. |
| PC-23552 |
(R)-ZG197
SaClpP agonist
|
(R)-ZG197 is a highly selective S. aureus caseinolytic protease P (SaClpP) activator / agonist with EC50 of 1.5 uM and Kd of 58 nM in BLI assays, 20-fold higher activity than that activates HsClpP. |
| PC-23551 |
ZG297
SaClpP agonist
|
ZG297 is a potent, selective S. aureus caseinolytic protease P (SaClpP) agonist with EC50 of 0.26 uM, without activity against Homo sapiens ClpP (HsClpP) (IC50>100 uM), exerts SaClpP-dependent antistaphylococcal activity. |
