Cat. No. |
Product Name |
Information |
PC-72489 |
LolCDE inhibitor compound 2A
LolCDE inhibitor
|
LolCDE inhibitor compound 2A is a small molecule inhibitor that inhibits the growth of P. aeruginosa by interfering with the function of the lipoprotein transport components LolCDE complex. |
PC-72426 |
MAC-545496
GraR inhibitor
|
MAC-545496 (MAC545496) is an antivirulence compound that reverses β-lactam resistance in the community-acquired MRSA USA300 strain via inhibition on GraR function (Kd<0.1 nM). |
PC-72420 |
KYT-1
Arg-gingipain inhibitor
|
KYT-1 is a potent, selective inhibitor of P. gingivalis virulence factor Arg-gingipain (Rgp) with Ki 40 nM (RgpA/B). |
PC-72419 |
KYT-36
Lysine-gingipain inhibitor
|
KYT-36 is a potent, selective, and bioavailable inhibitor of P. gingivalis virulence factor gingipain K (Kgp, lysine-gingipain), potently and selectively inhibits Kgp with Ki of 0.27 nM, respectively. |
PC-72418 |
COR588
Lysine-gingipain inhibitor
|
COR588 is a second-generation small-molecule lysine-gingipain (Kgp) inhibitor. |
PC-72417 |
COR388
Lysine-gingipain inhibitor
|
COR388 (Atuzaginstat) is an orally bioavailable, brain penetrant small-molecule that irreversibly inhibits lysine-gingipain (Kgp) with Ki of <0.01 nM. |
PC-72410 |
FIM1033
FimH inhibitor
|
FIM1033 (FIM-1033) is a potent small-molecule inhibitor of FimH with HAI EC90 of 8 nM, with antibiotica activities, significantly attenuated bacterial loads in pyelonephritis in treated mice. |
PC-72404 |
Compound 11726148
Antitubercular
|
Compound 11726148 is a potent, specific antitubercular agent against Mycobacterium tuberculosis (M. tb) with MIC of 0.05 ug/mL, targets cytochrome bc1 complex. |
PC-72403 |
Compound 11626252
Antitubercular
|
Compound 11626252 is a potent, specific antitubercular agent against Mycobacterium tuberculosis (M. tb) with MIC of 0.02 ug/mL, targets cytochrome bc1 complex. |
PC-72135 |
UAMC-03011
Anti-trypanosomal
|
UAMC-03011 is a potent anti-trypanosomal compound (IC50=0.63 uM, T. brucei). |
PC-72087 |
MRL-494
BamA inhibitor
|
MRL-494 (MRL494) is an antimicrobial small molecule that inhibits assembly of outer membrane proteins (OMPs) by the β-barrel assembly machine (BAM complex), inhibits the insertion of OMPs into the OM by targeting BamA. |
PC-72065 |
Fobrepodacin
Bacterial DNA gyrase inhibitor
|
Fobrepodacin (SR720) is the prodrof form of SPR719, mycobacterial DNA gyrase inhibitor. |