Cat. No. |
Product Name |
Information |
PC-62903 |
Imipenem
|
Imipenem (MK-0787) is a broad-spectrum, semi-synthetic beta-lactam carbapenem that has broad antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.. |
PC-62849 |
Pactamycin
|
Pactamycin (NSC 52947) is a potent protein synthesis inhibitor, inhibits protein synthesis at the translocation step on the 70S ribosome, has activity against Gram-positive and Gram-negative bacteria, and broad antitumor, antiviral, and antiplasmodial activity.. |
PC-62662 |
6-FABA
|
6-FABA (6-Fluoroanthranilic Acid) is a small-molecule inhibitor of MTB tryptophan synthesis that converts Mtb into a tryptophan auxotroph and restores the efficacy of a failed host defense. |
PC-62655 |
3-Cyanochromone
|
3-Cyanochromone is a potent gram-negative bacteria WcbL protein inhibitor with IC50 of 28 uM in a competitive enzyme-inhibition model, shows inhibition constants Ki of 10 uM.. |
PC-62606 |
DS-2969b
|
DS-2969b (DS 11960558) is a novel orally active GyrB inhibitor, inhibits the supercoiling activity of C. difficile DNA gyrase with IC50 of 20 ng/mL. |
PC-62532 |
NITD-564
|
NITD-564 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.59 uM, exhibits MIC50 of 160 nM against Mtb. |
PC-62531 |
NITD-916
|
NITD-916 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.57 uM, exhibits MIC50 of 50 nM against Mtb. |
PC-62513 |
G 0507
|
G 0507 is a novel inhibitor of the bacterial LolCDE ABC transporter, binds to LolCDE and stimulates its ATPase activity. |
PC-62349 |
1835F03
|
1835F03 is a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus, inhibits the growth of a panel of S aureus strains (MIC=1-3 ug/mL), including clinical MRSA isolates.. |
PC-62330 |
SMARt-420
|
SMARt-420 (BDM 41420) is a small molecule that can fully reverses ethionamide-acquired resistance and clears ethionamide-resistant M. tuberculosis infection in mice, also increases the basal sensitivity of bacteria to ethionamide.. |
PC-62185 |
FN075
|
FN075 is a small-molecule inhibitor targeting Escherichia coli amyloid biogenesis and biofilm formation. |
PC-62126 |
ML406
|
ML406 is a small molecule Mtb bioA (DAPA synthase) enzyme inhibitor (IC50=30 nM) that shows anti-tubercular activity, dispalys >100-fold selectivity over bioD. |