Cat. No. |
Product Name |
Information |
PC-63580 |
MsbA inhibitor 1
|
MsbA inhibitor 1 is a novel small molecule lipopolysaccharide biogenesis inhibitor, inhibits MsbA, an ATP-dependent flippase that translocates LPS across the inner membrane. |
PC-63533 |
XF-73
|
XF-73 (Exeporfinium chloride) is a novel broad-spectrum antibacterial agent that inhibits a range of gram-positive bacterial species (MIC=0.25-4 mg/mL), including Staphylococcus aureus. |
PC-63480 |
HMPC
|
HMPC is a novel bacteriostatic agent that shows bacteriostatic activity against S. aureus (MIC=4 μg/ml) and rescues Caenorhabditis elegans from S. aureus infection. |
PC-63351 |
LYS228
|
LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml. |
PC-63325 |
ANT431 sodium
|
ANT431 sodium is a novel, highly water-soluble metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2, shows a comparatively weak inhibitor of VIM-1 and IMP-1 (Ki of 14.6 and 4.15 uM, respectively). |
PC-63324 |
ANT431
|
ANT431 is a novel potent metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2, shows a comparatively weak inhibitor of VIM-1 and IMP-1 (Ki of 14.6 and 4.15 uM, respectively). |
PC-63297 |
VNRX-5133
|
VNRX-5133 is a highly potent and specific beta-lactamase inhibitor, for use in combination with a licensed beta-lactam antibiotic. |
PC-63264 |
RNPA2000
|
RNPA2000 is a small-molecule inhibitor of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing (IC50=130 uM). |
PC-43413 |
Rifaximin
|
Rifaximin is an oral, semi-synthetic antibiotic derived from Rifamycin SV with antibacterial activity, interferes with transcription by binding to the β-subunit of bacterial RNA polymerase. |
PC-43233 |
RNPA1000
|
RNPA1000 is a potent, specific small molecule inhibitor of S. aureus RnpA RNA degradation activity (IC50=100-125 uM), limits S. aureus mRNA turnover and growth. |
PC-43149 |
Tizoxanide
|
Tizoxanide is the main metabolite of nitazoxanide, which is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent.. |
PC-43054 |
Epetraborole hydrochloride
|
Epetraborole (GSK2251052, AN3365) is a broad-spectrum antibacterial inhibitor of leucyl tRNA-synthetase (LeuRS), shows MIC50/MIC90 of 2/4 ug/ml against 916 clinical anaerobic isolates. |