| Cat. No. |
Product Name |
Information |
| PC-27334 |
IGF2BP3-IN-2
IGF2BP3 inhibitor
|
IGF2BP3-IN-2 is a potent, selective small molecule inhibitor of RNA m6A reader insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) with IC50 of 0.12 uM in cellular thermal shift assay (CETSA). |
| PC-26565 |
GD433
NTMT1 inhibitor
|
GD433 is a potent, selective and substrate competitive inhibitor of N-terminal methyltransferase 1 (NTMT1) with IC50 of 27 nM. |
| PC-26383 |
(+)SHIN2
SHMT1/2 inhibitor
|
(+)SHIN2 is a folate-competitive, cell-permeable inhibitor of human SHMT1/2 with improved pharmacokinetic properties over SHIN1. |
| PC-26366 |
WDR5 oligomerization inducer WZ-1
WDR5 oligomerization inducer
|
WZ-1 is a selective WDR5 oligomerization inducer, binds the WBM site of WDR5 and reacts with Cys248 to form an intramolecular disulfide, triggers oligomerization via thio-disulfide exchange, disrupting WDR5 interactions at both WIN and WBM sites. |
| PC-25711 |
Heterochromatin protein 1 inhibitor (R)-18
HP1 inhibitor
|
Heterochromatin protein 1 inhibitor (R)-18 is a small-molecule inhibitor of heterochromatin protein 1 (HP1), inhibits the HP1/H3K9me3 interaction with IC50 of 18.1 uM. |
| PC-24895 |
KMT9 inhibitor 8
KMT9 inhibitor
|
KMT9 inhibitor 8 is the ethyl ester prodrug of KMT9 inhibitor 7b, a potent and selective lysine methyltransferase 9 (KMT9) inhibitor with Kd of 10 nM. |
| PC-23079 |
MS167
PRMT6 inhibitor
|
MS167 is a potent, selective and cell-active reversible PRMT6 inhibitor with IC50 of 28 nM. |
| PC-22808 |
AZ-PRMT5i-1
PRMT5 inhibitor
|
AZ-PRMT5i-1 is a potent, selective and MTA-cooperative PRMT5 inhibitor with IC50 of 5.5 nM in symmetrical dimethyl arginine methylation (SDMA) cellular imaging assay. |
| PC-22354 |
PRMT9 inhibitor LD2
PRMT9 inhibitor
|
PRMT9 inhibitor LD2 is a specific small molecule PRMT9 inhibitor, inhibits PABPC1 R493 methylation level with IC50 of 0.9 uM in in Molm13s, sparing other PRMTs. |
| PC-22311 |
WDR5 WIN site inhibitor C6 TFA
WDR5 inhibitor
|
WDR5 inhibitor C6 TFA is a highly potent WDR5 WIN site inhibitor with Kd of 0.1 nM.
|
